Synthesis and Characterization of Some Novel Mannich Base Compounds

Authors

Sivakumar P.R.
PG & Research Department of Chemistry, Government Arts College (Autonomous), Coimbatore - 641 018, Tamil Nadu, India
https://orcid.org/0000-0001-7182-9658
Sounthari P
Assistant Professor, Department of Chemistry, PSG College of Arts and Science, Coimbatore641 014, Tamil Nadu, India
https://orcid.org/0000-0002-0304-5576
DOI: https://doi.org/10.34256/

Keywords:

Green Chemistry, Mannich, formaldehyde, Secondary amines

Synopsis

The present study includes Synthesis of new Mannich base compounds based on some 1, 3, 5-riazine substituted uracil derivatives with formaldehyde and secondary amines. The title compounds were screened for their in vitro antimicrobial activity against Bacillus subtitle, Pseudonomous Aeruginosa, Staphylococcus aureoles and E.Colli and three fungal species Aspergillus niger, Candida Albicans and Aspergillus fumigatus using the disc diffusion method. Most of the synthesized compounds appeared with promising antimicrobial and antioxidant activity. The structure of the novel compounds were elucidated on the basis of IR, 1H and 13C NMR spectroscopy.

Published

December 12, 2019
Copyright (c) 2019 Sivakumar P.R., Sounthari P (Author)

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Details about this monograph

ISBN-13 (15)

978-93-89631-02-9

How to Cite

P.R., S., & P, S. (2019). Synthesis and Characterization of Some Novel Mannich Base Compounds. IOR INTERNATIONAL PRESS. https://doi.org/10.34256/